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Does Capilia Longa Really Work For Hair Loss?

Does Capilia Longa Really Work For Hair Loss?

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Why are you considering using Capilia Longa to tackle hair loss?

Capilia Longa is a turmeric-derived cosmetic ingredient that may help reduce hair loss and improve hair density. Early results are promising, but the reliability of these results is very limited, so long-term safety and true effectiveness are yet to be determined. Capilia Longa is an experimental hair loss ingredient that may help those affected by temporary hair loss conditions.

Executive summary

Discover what Capilia Longa is, how it may help with hair loss, what the current evidence says about its effectiveness and safety, and which products are available in the UK. Plus, compare Capilia Longa with minoxidil and other effective hair loss solutions.

Key takeaways

  • Capilia Longa is a patented, turmeric-derived cosmetic ingredient designed to stimulate activity within the hair follicle and reduce hair loss.

  • Early studies suggest Capilia Longa can help reduce hair loss when used in a formula alongside other ingredients, but evidence for its safety and effectiveness is very limited at present.

  • Minoxidil is generally a more reliable hair loss treatment than Capilia Longa, thanks to its expansive supporting body of evidence. Other hair loss treatment options include finasteride, microneedling, caffeine treatments, and hair transplants.

  • Speak to the friendly professional team at the Wimpole Clinic to find out which treatments are best suited to your type of hair loss.

What is Capilia Longa and how does it help with hair loss?

Capilia Longa is a cosmetic ingredient designed to help tackle hair loss. It’s derived from stem cells of the turmeric plant. Despite its natural origins, it’s patented by Vytrus Biotech, a Spanish biotechnology company. Vytrus claims that [1]:

“[Capilia Longa] produces an epigenetic reset of the hair bulb, re-starting the activity of dermal papilla cells thanks to the activity of Curcuma peptides, exosomes and Exopeptides™.”

That means Capilia Longa may be able to alter gene expression within the hair bulb to help minimise hair loss, without affecting the underlying DNA (although this has only been seen in lab studies so far, so the findings may be overstated). It can also stimulate activity within the hair follicle’s dermal papilla cells, which help regulate hair growth [2].

Curcuma peptides are derived from turmeric, and may have antimicrobial and antioxidant properties, while exosomes may act as an anti-inflammatory agent [3-4]. Exopeptides refer to a proprietary technology owned by Vytrus, and it’s said to “power” Capilia Longa, though it’s unclear exactly how (or if) this works [5].

Antioxidants, anti-inflammatories, and antimicrobials can help with hair loss, especially if it’s driven by oxidative stress, follicular inflammation, or bacterial infection [6-7]. However, it’s unlikely to stop or reverse balding caused by pattern hair loss, as this is driven mostly by genetics and hormones.

What results can you expect when using Capilia Longa?

As of 2026, the evidence for using Capilia Longa for hair growth is pretty limited, though there are some signs that Capilia Longa may help reduce hair loss and improve hair thickness, especially when used alongside other proven ingredients.

One study found that a combination of Capilia Longa, peptides, and stem cell-derived nutrients led to a 23.9% reduction in hair loss in women affected by telogen effluvium [8]. Another found that a serum containing Capilia Longa (along with several other ingredients) led to improved hair growth, density, thickness, and strength [9].

However, two small, short studies don’t provide conclusive evidence for Capilia Longa’s effectiveness. Much larger studies are needed to establish true safety and efficacy. And it’s important to be wary of information presented as evidence when it hasn’t been peer-reviewed or otherwise independently verified (such as Vytrus’s study results that claim Capilia Longa can reduce hair loss by up to 89%) [10].

  • Study [8] compared the efficacy and safety of a formula containing Capilia Longa against two other formulas. Participants included 45 women experiencing telogen effluvium, and results were monitored over 90 days.
  • Researchers concluded that the Capilia Longa formula reduced hair loss by 23.9% over the 90 day period. This was the least effective of the three compared groups.
  • Study [9] researched the safety and efficacy of Regendil, a formula consisting of Capilia Longa, Redensyl, AnaGain and Procapil). 32 people with hair loss were enrolled in the study, and were required to apply 0.5 ml of Regendil to their scalp once a day for 60 days.
  • Hair growth improved by 1.5 times after 60 days, with the hair growth rate increasing by 31.62% over the same time. However, it’s not possible to know the extent to which Capilia Longa itself contributed to these results.

What are the side effects of Capilia Longa?

Both studies exploring the use of Capilia Longa for hair loss reported good tolerability, with no adverse effects reported [8-9]. But more research is needed to confirm that Capilia Longa is well-tolerated among the wider population.

Although Capilia Longa is a naturally-derived ingredient, turmeric is known to cause skin irritation and even allergic reactions when applied topically [11]. So it’s best to test a small amount of the product on your skin before applying it across your scalp.

Capilia Longa vs minoxidil: which is best for treating hair loss?

Unlike Capilia Longa, which is a relatively new and untested ingredient, minoxidil is a well-established treatment for hair loss. Explore how minoxidil measures up against Capilia Longa in the table below.

CriteriaCapilia LongaMinoxidil
Ingredient origin Naturally derived from turmeric rootPharmaceutical product
Application method TopicalTopical or oral
Types of hair loss Telogen effluviumPattern hair loss, telogen effluvium, alopecia areata, non-scarring alopecias
Possible results Unknown for Capilia Longa alone; may reduce hair loss and improve density when combined with other proven proprietary ingredients [8-9].Strong track record of producing a significant increase in hair density [12-13].
Side effects None knownFor topical minoxidil, known side effects include skin irritation, temporary reversible hair loss, and mild facial hair growth [12].
How it works Said to minimise hair loss by altering gene expression within the hair bulb and stimulating activity in the hair follicle’s dermal papilla cells [1].Vasodilation — minoxidil widens the blood vessels in the scalp, allowing more oxygen and nutrients to reach the follicles. It can also lengthen the anagen phase of the hair growth cycle [12].
How long it takes to work2+ months (when used in conjunction with other ingredients) [8-9]2+ months [14]
AvailabilityOver-the-counter hair loss serumsOver-the-counter

Overall, minoxidil is a more reliable choice than Capilia Longa for most people affected by hair loss. It has a larger body of evidence to support its use, and is suitable for multiple types of alopecia, including male pattern baldness and female pattern hair loss. More is known about the side effects of minoxidil, and users can potentially mitigate these by choosing a lower concentration product like minoxidil 2%.

If you’re looking for a more natural, non-pharmaceutical way to tackle hair loss, Capilia Longa may be an option. However, it’s also a good idea to consider other proprietary ingredients, such as Capixyl, AnaGain, and Baicapil. Many commercially available serums contain multiple ingredients alongside Capilia Longa.

Which Capilia Longa products are available?

Capilia Longa isn’t a controlled ingredient, so you can buy hair density serums containing Capilia Longa online or over-the-counter. The products below are available in the UK as of October 2026, and contain Capilia Longa as a hair growth active.

Note: The Wimpole Clinic isn’t affiliated with the cosmetic hair treatment manufacturers or sellers below. We don’t get commission if you buy any of the listed products.

Australian Bodycare Biotin Hair Loss Serum

Active ingredients: Capilia Longa, biotin, caffeine, niacinamide

Cost: £14.99 for 100 ml

How to apply: Apply the serum to thinning areas on your scalp morning and night. Massage into your skin to ensure even distribution of the product.

What to know: Caffeine is a proven treatment for hair loss, especially when used as a leave-on ingredient [15]. Topical biotin is often touted as a hair growth enhancer, but there’s not much evidence behind this claim. Early evidence suggests niacinamide may help promote hair growth, though more research is needed to confirm this [16].

Odenson Hair Growth Serum

Active ingredients: Capilia Longa, GHK-Cu copper peptides

Cost: £29.90 for a 50 day supply (100 ml)

How to apply: Apply 2-3 pumps of serum to thinning areas of your scalp once a day. Ideally leave at least 8-12 hours before washing your hair after serum application.

What to know: While copper peptides can help with hair loss, there are unresolved challenges with delivering the benefits of this ingredient through topical application [17]. So don’t overrely on this to produce significant hair growth effects.

Scandinavian BioLabs Bio-Pilixin Activation Serum

Active ingredients: Capilia Longa, niacinamide, HotFlux

Cost: From £47.00 for 100 ml (one-time purchases cost more)

How to apply: Apply 3 ml of the serum to your scalp every day and massage it into the skin.

What to know: HotFlux is a proprietary warming agent that’s said to increase blood flow to the scalp, though there’s limited evidence for this ingredient as a hair loss treatment. Expect your scalp to feel warm and tingly after application.

Proven ways to treat hair loss

Early evidence for Capilia Longa is promising, but there are many hair loss solutions with significantly more evidence to support their use. Here are the best proven ways to treat hair loss:

  • Minoxidil — Suitable for most types of non-scarring hair loss, minoxidil is a low-stakes, entry-level option. It doesn’t affect your hormone levels and side effects are mostly limited to skin irritation symptoms like redness, flaking, and itchiness.
  • Finasteride — Finasteride is a licensed treatment for male pattern baldness. It’s one of the best ways to preserve your hair, but can have significant side effects, so speak to a doctor about trying finasteride for hair loss.
  • Caffeine shampoos and serums — Caffeine has been shown to reduce hair loss when used consistently over several months [15]. It’s available over-the-counter, and is often combined with other ingredients to boost hair growth.
  • Microneedling — Microneedling or derma rolling for hair loss triggers wound healing mechanisms that can help limit hair loss and promote regrowth. It can also increase absorption of topical serums and solutions, so it works well in conjunction with other treatments.
  • Dutasteride — Dutasteride is an off-label treatment for male pattern baldness. It works in a similar way to finasteride, but it’s currently not licensed in the same way. Speak to a doctor if you’re interested in using dutasteride for hair loss.
  • FUE and FUT hair transplants — Surgical options are usually reserved for those with permanent, irreversible hair loss stemming from pattern baldness. FUE and FUT can replace lost hair permanently, giving you lifelong results.

Hair loss treatment advice from the Wimpole Clinic

Whether you’re noticing the early signs of hair thinning or experiencing established, advanced hair loss, the Wimpole Clinic can help.

As one of the world’s longest-running hair transplant clinics, we have more than 50 years’ experience treating hair loss with surgical and non-surgical methods. And with free consultation available at our UK-wide and international clinic locations, you can get honest expert advice on your hair loss.

Discover more about your hair loss treatment options when you book a consultation at the Wimpole Clinic. We’ll discuss how to preserve your hair, what you can do about permanent hair loss, and when to expect results from any treatments you decide to use.

Does Capilia Longa Really Work For Hair Loss?, Wimpole Clinic

FAQs

Learn how long to use Capilia Longa, whether it works for eyebrows, and more in our Capilia Longa FAQs.

There’s not much data available about the long-term safety of using Capilia Longa. It’s a naturally-derived product, so it’s unlikely that any significant safety concerns will be discovered about its long term use. But this can’t be guaranteed, so take this into account when deciding whether to use products containing Capilia Longa.

No topical or oral hair loss treatment continues to provide clinical benefits when you stop using it. So if you stop using a product containing Capilia Longa, expect any hair loss to continue after a while.

Vytrus suggests that Capilia Longa can enhance eyebrow and eyelash density, though there’s no independent research to verify this. There’s much stronger evidence for other eyelash/eyebrow growth treatments like bimatoprost and minoxidil [18-19].

The Vytrus formula tested on eyebrows and eyelashes is likely to differ from commercially available products containing Capilia Longa, so it’s best not to use these products on or around your eyes.

No studies have directly compared Capilia Longa vs finasteride, but finasteride is likely to be far more effective for men with male pattern baldness. Finasteride works by limiting the amount of dihydrotestosterone in your body, as this hormone binds to receptors in the hair follicles and causes them to shrink.

Capilia Longa doesn’t appear to have any hormonal effect, so it’s unlikely it would have a significant impact on male pattern baldness symptoms. However, it may help reduce symptoms of stress-related hair loss, which finasteride won’t help with.

Capilia Longa is derived from turmeric, but it’s not the same as turmeric powder or the turmeric root. Capilia Longa is the concentrated secretome of specific cells from the turmeric root.

Capilia Longa is most likely to be effective in those with telogen effluvium — temporary hair loss stemming from stress, trauma, and other psychological or physiological triggers. In many cases, telogen effluvium is short-lived and resolves by itself, but treatments like Capilia Longa may help encourage regrowth.

Sources:
  1. Vytrus Biotech. (n.d.). Capilia Longa™: Make your hair sprout again. https://www.vytrus.com/natural-active/capilia-Longa/.
  2. Driskell, R. R., Clavel, C., Rendl, M., & Watt, F. M. (2011). Hair follicle dermal papilla cells at a glance. Journal of cell science, 124(Pt 8), 1179–1182. https://doi.org/10.1242/jcs.082446.
  3. Roytrakul, S., Charoenlappanit, S., Kittisenachai, S., Siangpro, N., Sichaem, J., Chuakrut, S., Sarin, S., & Jutakanoke, R. (2024). Antimicrobial and antioxidant activities of peptide derived from turmeric plant (Curcuma Longa L). PloS one, 19(11), e0314482. https://doi.org/10.1371/journal.pone.0314482.
  4. Sun, D. (2010). Exosomal curcumin: Its bioavailability and potential anti-inflammation activity [Doctoral dissertation, University of Alabama at Birmingham]. UAB Digital Commons. https://digitalcommons.library.uab.edu/etd-collection/3069/.
  5. Vytrus Biotech. (n.d.). Vytrus Biotech trademarks Exopeptides technology to lead the plant exosome revolution. https://www.vytrus.com/vytrus-biotech-trademarks-exopeptides-technology-to-lead-the-plant-exosome-revolution/.
  6. Davis, M. G., Piliang, M. P., Bergfeld, W. F., Caterino, T. L., Fisher, B. K., Sacha, J. P., Carr, G. J., Moulton, L. T., Whittenbarger, D. J., & Schwartz, J. R. (2021). Scalp application of antioxidants improves scalp condition and reduces hair shedding in a 24-week randomized, double-blind, placebo-controlled clinical trial. International journal of cosmetic science, 43 Suppl 1, S14–S25. https://doi.org/10.1111/ics.12734.
  7. Bin Rubaian, N. F., Alzamami, H. F. A., & Amir, B. A. (2024). An Overview of Commonly Used Natural Alternatives for the Treatment of Androgenetic Alopecia, with Special Emphasis on Rosemary Oil. Clinical, cosmetic and investigational dermatology, 17, 2495–2503. https://doi.org/10.2147/CCID.S470989.
  8. Chandrashekar, B. S., Roopa, M. S., Kusuma, M. R., Madura, C., Shenoy, C., Narayna, N. L., & Ghoshal, P. (2025). Comparative analysis of various hair peptide serums in managing telogen effluvium in females: Efficacy, safety, and patient satisfaction. Journal of Cutaneous and Aesthetic Surgery, 18(4). https://doi.org/10.25259/JCAS_138_2024.
  9. Merja, A., Patel, N., Patel, M., Patnaik, S., Ahmed, A., & Maulekhi, S. (2024). Safety and efficacy of REGENDIL™ infused hair growth promoting product in adult human subject having hair fall complaints (alopecia). Journal of cosmetic dermatology, 23(3), 938–948. https://doi.org/10.1111/jocd.16084.
  10. Vytrus Biotech. (2016, November 21). Vytrus Biotech unveils Capilia Longa – the hair 3D Bio-printer. Cosmetics Business. https://www.cosmeticsbusiness.com/news/article_page/Vytrus_Biotech_unveils_Capilia_Longa_the_hair_3D_Bio-printer/123105/.
  11. Palaniappan, V., & Karthikeyan, K. (2022). Turmeric: The Yellow Allergen. Indian dermatology online journal, 14(4), 459–464. https://doi.org/10.4103/idoj.idoj_340_22.
  12. Suchonwanit, P., Thammarucha, S., & Leerunyakul, K. (2019). Minoxidil and its use in hair disorders: a review. Drug design, development and therapy, 13, 2777–2786. https://doi.org/10.2147/DDDT.S214907.
  13. Rundegren, J. (2004). A one-year observational study with minoxidil 5% solution in Germany: Results of independent efficacy evaluation by physicians and patients. Journal of the American Academy of Dermatology, 50(3 Suppl.), P91. https://doi.org/10.1016/j.jaad.2003.10.289.
  14. Vañó-Galván, S., Pirmez, R., Hermosa-Gelbard, A., Moreno-Arrones, Ó. M., Saceda-Corralo, D., Rodrigues-Barata, R., Jimenez-Cauhe, J., Koh, W. L., Poa, J. E., Jerjen, R., Trindade de Carvalho, L., John, J. M., Salas-Callo, C. I., Vincenzi, C., Yin, L., Lo-Sicco, K., Waskiel-Burnat, A., Starace, M., Zamorano, J. L., … Bhoyrul, B. (2021). Safety of low-dose oral minoxidil for hair loss: A multicenter study of 1404 patients. Journal of the American Academy of Dermatology, 84(6), 1644–1651. https://doi.org/10.1016/j.jaad.2021.02.054.
  15. Szendzielorz, E., & Spiewak, R. (2025). Caffeine as an Active Ingredient in Cosmetic Preparations Against Hair Loss: A Systematic Review of Available Clinical Evidence. Healthcare (Basel, Switzerland), 13(4), 395. https://doi.org/10.3390/healthcare13040395.
  16. Choi, Y. H., Shin, J. Y., Kim, J., Kang, N. G., & Lee, S. (2021). Niacinamide Down-Regulates the Expression of DKK-1 and Protects Cells from Oxidative Stress in Cultured Human Dermal Papilla Cells. Clinical, cosmetic and investigational dermatology, 14, 1519–1528. https://doi.org/10.2147/CCID.S334145.
  17. Liu, T., Liu, Y., Zhao, X., Zhang, L., Wang, W., Bai, D., Liao, Y., Wang, Z., Wang, M., & Zhang, J. (2023). Thermodynamically stable ionic liquid microemulsions pioneer pathways for topical delivery and peptide application. Bioactive materials, 32, 502–513. https://doi.org/10.1016/j.bioactmat.2023.10.002.
  18. Chanasumon, N., Sriphojanart, T., & Suchonwanit, P. (2018). Therapeutic potential of bimatoprost for the treatment of eyebrow hypotrichosis. Drug design, development and therapy, 12, 365–372. https://doi.org/10.2147/DDDT.S156467.
  19. Lee, S., Tanglertsampan, C., Tanchotikul, M., & Worapunpong, N. (2014). Minoxidil 2% lotion for eyebrow enhancement: a randomized, double-blind, placebo-controlled, spilt-face comparative study. The Journal of dermatology, 41(2), 149–152. https://doi.org/10.1111/1346-8138.12275.

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